Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SPR | P35270 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28211550 | 0.79 | DRD4 (0.39) | DRD4AOC3L3MBTL1HSD17B10NOS3 | |
| SCHEMBL498175 | 0.78 | — | — | |
| SCHEMBL12539252 | 0.77 | DRD4 (0.43) | DRD4AOC3SPRNOS3NOS2 | |
| SCHEMBL15025455 | 0.77 | DRD4 (0.41) | DRD4AOC3RBP4L3MBTL1SPR | |
| SCHEMBL4562941 | 0.75 | DRD4 (0.46) | DRD4AOC3RBP4SPRHSD17B10 | |
| SCHEMBL20738510 | 0.74 | DRD4 (0.47) | DRD4AOC3CNR1CNR2RBP4 | |
| SCHEMBL577126 | 0.74 | — | — | |
| SCHEMBL497630 | 0.74 | TSHR (0.38) | DRD4AOC3HSD17B10NOS3NOS2 | |
| SCHEMBL3654356 | 0.73 | DRD4 (0.41) | DRD4AOC3RBP4SPRNOS3 | |
| SCHEMBL13407392 | 0.73 | DRD4 (0.49) | DRD4AOC3SPRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090304632-A1 | HETEROCYCLIC NF-kB INHIBITORS | 4SC AG (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090304632-A1 | HETEROCYCLIC NF-kB INHIBITORS | NFKBIA, NFKB2, IKBKB | DRD4 1791/4885AOC3 166/4885CNR1 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.