Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | DDX3X | O00571 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16943226 | 0.88 | MAPT (0.56) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL5880840 | 0.86 | ALDH1A1 (0.56) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL730213 | 0.86 | MAPT (0.62) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL29689011 | 0.85 | KMT2A (0.61) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL2010242 | 0.83 | MAPT (0.56) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL30067720 | 0.83 | KMT2A (0.58) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL3214047 | 0.83 | KMT2A (0.58) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL8223354 | 0.83 | MEN1 (0.54) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL29780605 | 0.83 | MEN1 (0.54) | MAPTMEN1POLBKMT2ADDX3X | |
| SCHEMBL4611265 | 0.82 | ALDH1A1 (0.52) | MAPTMEN1POLBKMT2ADDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107840826-A | 1H-indazole derivatives and application thereof as IDO (intermediate bonded oxygen) inhibitor | 西华大学 | 2018-03-27 | — | — | CN | disclosed |
| CN-107805221-A | Method for preparing 1H-indazole derivative | 西华大学 | 2018-03-16 | — | — | CN | disclosed |