Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315315 | 0.81 | MAOB (0.52) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL5572358 | 0.76 | MAOB (0.46) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL6745723 | 0.76 | MAOB (0.46) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL6326692 | 0.72 | MAOB (0.60) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL23524584 | 0.71 | MAOB (0.52) | TAAR1SLC6A2MAOBLOXL2SMN1; SMN2 | |
| SCHEMBL144711 | 0.71 | MAOB (0.52) | TAAR1SLC6A2MAOBLOXL2TP53 | |
| SCHEMBL5577579 | 0.70 | TAAR1 (0.59) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL516033 | 0.69 | TAAR1 (0.73) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL2487465 | 0.69 | TAAR1 (0.73) | TAAR1SLC6A2CYP2D6CYP1A2CYP3A4 | |
| Benzene SCHEMBL1226361 | 0.69 | MAOB (0.70) | TAAR1SLC6A2MAOBHTR2ALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658732-B | The metallic effect pigments being modified with the silylation layer comprising at least two different difunctional silanes | 舒伦克金属颜料有限公司 | 2018-05-04 | — | — | CN | disclosed |