SCHEMBL2487465

SCHEMBL2487465

CC(N)(N)Cc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.73
SLC6A2 P23975 3/20 0.73
CYP2D6 P10635 2/20 0.54
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
HIF1A Q16665 1/20 0.52
TRPA1 O75762 1/20 0.47
CYP1A2 P05177 3/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
TP53 P04637 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.43
CYP3A4 P08684 2/20 0.43
PRMT1 Q99873 1/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
HTR2A P28223 1/20 0.43
HRH1 P35367 1/20 0.43
HTR2B P41595 1/20 0.43
CHRNA4 P43681 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL516033 0.84 TAAR1 (0.73) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Phentermine SCHEMBL26615 0.84 SLC6A2 (1.00) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Phentermine SCHEMBL10392295 0.84 SLC6A2 (1.00) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Phentermine SCHEMBL3676484 0.82 SLC6A2 (0.95) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Ammonia Solution, Strong SCHEMBL2477835 0.82 SLC6A2 (0.70) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Phentermine SCHEMBL28695767 0.82 SLC6A2 (0.95) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Phentermine SCHEMBL41585 0.82 SLC6A2 (0.95) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Phentermine SCHEMBL28729624 0.82 SLC6A2 (0.95) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
SCHEMBL10503241 0.80 TAAR1 (0.67) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2
Phentermine SCHEMBL25214698 0.80 SLC6A2 (0.91) TAAR1SLC6A2CYP2D6LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1017358-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-07-12 EP claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO claimed
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS INC (US) 2025-11-27 US disclosed
EP-4472995-A2 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2024-12-11 EP disclosed
WO-2023150618-A2 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2023-08-10 WO disclosed
EP-3700922-A1 VESICLE INCORPORATING TRANSMEMBRANE PROTEIN Aquaporin A/S (DK) 2020-09-02 EP disclosed
WO-2020162418-A1 COLORLESS TRANSPARENT POLYIMIDE FILM 三菱瓦斯化学株式会社 2020-08-13 WO disclosed
EP-3212183-A1 SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS University of Rochester (US) 2017-09-06 EP disclosed
WO-2016070021-A1 SYNERGISTIC COMPOSITIONS FOR TREATING MICROBIAL INFECTIONS UNIVERSITY OF ROCHESTER (US) 2016-05-06 WO disclosed
CN-103172531-B Diphenylamine compound, polyamic acid composition prepared from diphenyl amine compound, polyimide composition and liquid crystal alignment agent DAXIN MATERIALS CORP. (CN) 2016-01-20 CN disclosed
CN-104292184-A Phenylenediamine compound, polymer, composition for alignment film, and liquid crystal display module DAXIN MATERIALS CORP 2015-01-21 CN disclosed
EP-0948496-A2 SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE Amgen inc. (US) 1999-10-13 EP disclosed
EP-0929563-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY Abbott Laboratories (US) 1999-07-21 EP disclosed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO disclosed
EP-0876388-A1 TRICYCLIC ERYTHROMYCIN DERIVATIVES Abbott Laboratories (US) 1998-11-11 EP disclosed
WO-1998030574-A1 TRICYCLIC ERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 1998-07-16 WO disclosed
WO-1998024780-A2 SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE AMGEN INC. (US) 1998-06-11 WO disclosed
WO-1998009978-A1 6-O-SUBSTITUTED KETOLIDES HAVING ANTIBACTERIAL ACTIVITY ABBOTT LABORATORIES (US) 1998-03-12 WO disclosed
WO-1997017356-A1 TRICYCLIC ERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 1997-05-15 WO disclosed
US-4289885-A 3-[2-(Dimethylamino)-2-phenylethyl]N-[phenylamino)carbonyl]sydnone imine, a new central nervous system stimulant AMERICAN HOME PRODUCTS CORPORATION (US) 1981-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF TAAR1 3031/4885SLC6A2 3658/4885CYP2D6 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.