Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15202847 | 0.92 | EPHX1 (0.72) | EPHX1KMT2AHPGDPOLBGNAI3 | |
| SCHEMBL13484250 | 0.92 | EPHX1 (0.60) | EPHX1KMT2AHPGDPOLBGNAI3 | |
| SCHEMBL6473627 | 0.91 | EPHX1 (0.76) | EPHX1KMT2AHPGDPOLBGNAI3 | |
| SCHEMBL4098357 | 0.85 | KMT2A (0.72) | EPHX1KMT2AHPGDEPHX2SMN1; SMN2 | |
| SCHEMBL3231741 | 0.84 | EPHX1 (0.51) | EPHX1KMT2AHPGDPOLBGNAI3 | |
| SCHEMBL9344976 | 0.82 | EPHX1 (0.43) | EPHX1KMT2AHPGDPOLBGNAI3 | |
| SCHEMBL24342375 | 0.82 | KMT2A (0.57) | EPHX1KMT2AHPGDGNAI3GNAO1 | |
| SCHEMBL22813414 | 0.81 | EPHX1 (0.80) | EPHX1KMT2AHPGDEPHX2SMN1; SMN2 | |
| SCHEMBL12636381 | 0.81 | SLC6A1 (0.58) | EPHX1KMT2AHPGDPOLBGNAI3 | |
| SCHEMBL34468320 | 0.80 | EPHX1 (0.66) | EPHX1KMT2AHPGDPOLBGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949558-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-107949558-A | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2018-04-20 | — | — | CN | disclosed |