SCHEMBL28212809

SCHEMBL28212809

NNc1cccc[n+]1[O-].[Zn]

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
IDO1 P14902 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGS2 P35354 1/20 0.33
KDM4E B2RXH2 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1620966 0.98
SCHEMBL5076504 0.74
SCHEMBL10504892 0.71 GAA (0.40) LMNAHTTTDP1CYP1A2CYP3A4
SCHEMBL6951347 0.71 CA12 (0.38) LMNAHTTTDP1IDO1KDM4E
SCHEMBL18155945 0.70 MAPT (0.41) LMNAHTTTDP1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL3565750 0.70 HSD17B10 (0.44) LMNAHTTTDP1CYP1A2CYP3A4
SCHEMBL31105800 0.70 ALDH1A1 (0.41) LMNAHTTTDP1KDM4EKMT2A
SCHEMBL17627325 0.68 KDM4E (0.41) LMNAHTTTDP1CYP1A2CYP2C19
SCHEMBL11316710 0.67 HSD17B10 (0.45) TDP1CYP1A2CYP2C19KDM4EKMT2A
SCHEMBL11554884 0.67 HSD17B10 (0.40) HTTTDP1CYP3A4IDO1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105979926-B Capryloyl alanine ethylester as penetration enhancer 巴斯夫欧洲公司 2019-09-27 CN disclosed
CN-105722818-B Betaine ester and its preparation method and application 伊士曼化工公司 2019-04-23 CN disclosed
CN-105102525-B Rheology modifier 阿克佐诺贝尔化学国际公司 2019-04-16 CN disclosed
CN-104116646-B Concentrated type personal cleaning compositions 宝洁公司 2018-08-17 CN disclosed
CN-105026118-B Article for carrying a glide member for use with a razor 吉列有限责任公司 2018-06-12 CN disclosed
CN-103221030-B Intermediates and surfactants for household cleaning and personal care compositions, and methods for making the same 宝洁公司 2018-05-29 CN disclosed