SCHEMBL28212908

SCHEMBL28212908

Nc1ncc2c(Cl)c(Cl)ccc2n1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCL6 P41182 1/20 0.41
DHFR P00374 1/20 0.41
GRM4 Q14833 1/20 0.40
ADORA1 P30542 1/20 0.40
CYP2A6 P11509 1/20 0.36
EPHB4 P54760 1/20 0.35
TEK Q02763 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL28212380 0.90 PDGFRB (0.37) BCL6DHFRGRM4ADORA1
SCHEMBL30637864 0.81 GRM4 (0.38) BCL6GRM4
SCHEMBL26679767 0.81 GRM4 (0.38) BCL6GRM4
SCHEMBL28212909 0.81 PDGFRB (0.37)
SCHEMBL559893 0.77 MAPT (0.47) BCL6DHFRGRM4ADORA1
SCHEMBL26679797 0.71 EGFR (0.32)
SCHEMBL2337174 0.69 SMN1; SMN2 (0.61) DHFRADORA1CYP2A6
SCHEMBL29516287 0.69 BCL6 (0.41) BCL6ADORA1TEK
SCHEMBL29224063 0.69 BCL6 (0.41) BCL6ADORA1TEK
SCHEMBL30628471 0.68 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107903217-A A kind of preparation method of anagrelide impurity B 湖北省宏源药业科技股份有限公司 2018-04-13 CN claimed
CN-107903217-A A kind of preparation method of anagrelide impurity B 湖北省宏源药业科技股份有限公司 2018-04-13 CN disclosed