⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336218 | 0.70 | CA4 (0.37) | — | |
| SCHEMBL1521464 | 0.67 | — | — | |
| SCHEMBL2916903 | 0.62 | — | — | |
| SCHEMBL10193973 | 0.62 | — | — | |
| SCHEMBL5846213 | 0.58 | — | — | |
| SCHEMBL5836218 | 0.58 | — | — | |
| Trimethylammonium SCHEMBL27327046 | 0.58 | ALDH1A1 (0.35) | — | |
| SCHEMBL27761909 | 0.57 | — | — | |
| SCHEMBL21526609 | 0.57 | — | — | |
| SCHEMBL27461185 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922413-A | Novel 6-6 bicyclic aromatic ring substituted nucleoside analogs as PRMT5 inhibitors | 詹森药业有限公司 | 2018-04-17 | — | — | CN | disclosed |