Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968423 | 0.84 | CA12 (0.55) | LMNAMMP8PIN1MEN1NPC1 | |
| Acetic Acid SCHEMBL27299232 | 0.84 | LMNA (0.50) | LMNAMMP8KMT2AALDH1A1RECQL | |
| SCHEMBL1332017 | 0.84 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL1331748 | 0.84 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL1330728 | 0.84 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL1332187 | 0.84 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL81193 | 0.84 | LMNA (0.53) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL27616702 | 0.83 | LMNA (0.50) | LMNAMMP8PIN1MEN1NPC1 | |
| Iodide SCHEMBL5351689 | 0.83 | CA12 (0.54) | LMNAMMP8PIN1MEN1NPC1 | |
| Bromide SCHEMBL7614615 | 0.83 | CA12 (0.54) | LMNAMMP8PIN1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107847485-A | 5-methoxytryptophan and derivatives and application thereof | 财团法人卫生研究院 | 2018-03-27 | — | — | CN | disclosed |