SCHEMBL28213865

SCHEMBL28213865

O=C(O)COC(C(=O)O)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
SLC1A3 P43003 3/20 0.38
SLC1A2 P43004 3/20 0.38
SLC1A1 P43005 3/20 0.38
EPHX1 P07099 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
TSHR P16473 1/20 0.33
CTH P32929 1/20 0.33
CBS P35520 1/20 0.33
THPO P40225 1/20 0.33
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
DPP4 P27487 1/20 0.33
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24328850 0.81 TSHR (0.40) ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1
SCHEMBL8162895 0.81 TSHR (0.40) ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1
SCHEMBL23247540 0.78 TSHR (0.38) ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1
SCHEMBL24328845 0.78 TSHR (0.38) ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1
SCHEMBL31355393 0.77 EPHX1 (0.43) ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1
SCHEMBL6691169 0.77 ALDH1A1 (0.42) ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1
Hydrochloric Acid SCHEMBL2746410 0.76 ALDH1A1 (0.44) ALDH1A1SLC1A3SLC1A2SLC1A1EPHX1
SCHEMBL24328846 0.74 EPHX1 (0.40) ALDH1A1EPHX1NPSR1CYP2C9CYP2C19
SCHEMBL1050728 0.74 EPHX1 (0.40) ALDH1A1EPHX1NPSR1CYP2C9CYP2C19
SCHEMBL1050730 0.74 EPHX1 (0.40) ALDH1A1EPHX1NPSR1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108828033-A A kind of solid ionic electrodes selective and preparation method based on single corner electrode 浙江大学 2018-11-16 CN disclosed
CN-107884459-A A kind of solid ionic electrodes selective based on single corner electrode and preparation method thereof 浙江大学 2018-04-06 CN disclosed