Acrylamide

Acrylamide

SCHEMBL28214663

C=CC(=O)OCCC#N.C=CC(N)=O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.48
ALDH1A1 P00352 6/20 0.48
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP3A4 P08684 2/20 0.48
HSD17B10 Q99714 1/20 0.48
HPGD P15428 1/20 0.44
FGFR4 P22455 1/20 0.41
THRB P10828 2/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
MCL1 Q07820 1/20 0.31
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33946 0.92
Lithium SCHEMBL30027291 0.90 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
Butadiene SCHEMBL10894736 0.89 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid SCHEMBL21799261 0.87 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1067821 0.86 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9472105 0.84 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20796901 0.82 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30540307 0.82 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL8413578 0.81 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL303363 0.81 TSHR (0.70) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108025540-A Laminated film and laminated molded article 三菱化学株式会社 2018-05-11 CN disclosed