Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285701 | 0.98 | — | — | |
| SCHEMBL6284235 | 0.93 | KDM4E (0.44) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL6284516 | 0.91 | KDM4E (0.48) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL1309431 | 0.84 | TDP1 (0.42) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL6284265 | 0.83 | TSHR (0.39) | KDM4E | |
| SCHEMBL6286323 | 0.82 | — | — | |
| SCHEMBL1837224 | 0.79 | KDM4E (0.48) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL12522288 | 0.78 | KDM4E (0.64) | KDM4EMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL20031214 | 0.77 | CA3 (0.48) | KDM4EMAPK1HIF1APAOXTDP1 | |
| SCHEMBL11231320 | 0.77 | EPHX1 (0.54) | KDM4EMAPK1HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107964081-A | One kind is low to distribute response type tertiary amine catalyst and its preparation method and application | 万华化学集团股份有限公司 | 2018-04-27 | — | — | CN | disclosed |