SCHEMBL28214845

SCHEMBL28214845

NCCOC(=O)c1ccccc1C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.61
TSHR P16473 8/20 0.55
TDP1 Q9NUW8 5/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
ALOX15 P16050 1/20 0.52
CYP3A4 P08684 4/20 0.51
MAPK1 P28482 3/20 0.51
TP53 P04637 2/20 0.51
HSD17B10 Q99714 3/20 0.50
NPC1 O15118 3/20 0.50
HPGD P15428 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GLA P06280 1/20 0.50
HIF1A Q16665 1/20 0.50
LMNA P02545 1/20 0.50
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28393082 0.92 ALDH1A1 (0.64) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL3302489 0.88 ALDH1A1 (0.69) ALDH1A1TSHRTDP1L3MBTL1ALOX15
SCHEMBL4280939 0.88 TSHR (0.60) ALDH1A1TSHRTDP1L3MBTL1ALOX15
SCHEMBL28492073 0.86 ALDH1A1 (0.67) ALDH1A1TSHRTDP1L3MBTL1ALOX15
SCHEMBL27446307 0.85 TSHR (0.67) ALDH1A1TSHRTDP1L3MBTL1ALOX15
SCHEMBL5709795 0.85 TSHR (0.70) ALDH1A1TSHRTDP1L3MBTL1ALOX15
Phthalic Acid SCHEMBL30122831 0.84 ALDH1A1 (0.74) ALDH1A1ALOX15HSD17B10HPGDSMN1; SMN2
Phthalic Acid SCHEMBL8162329 0.84 ALDH1A1 (0.74) ALDH1A1ALOX15HSD17B10HPGDSMN1; SMN2
Phthalic Acid SCHEMBL30999729 0.84 ALDH1A1 (0.74) ALDH1A1ALOX15HSD17B10HPGDSMN1; SMN2
Phthalic Acid SCHEMBL29039922 0.84 ALDH1A1 (0.74) ALDH1A1ALOX15HSD17B10HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109180048-B Nano precursor medium transmission inhibitor and preparation method thereof 江苏苏博特新材料股份有限公司 2021-12-17 CN disclosed
CN-106008238-B Double Diethylaminoethanol ester citrate compounds of plant growth regulator phthalic acid and preparation method thereof 苏州科技大学 2018-05-04 CN disclosed