SCHEMBL28215

SCHEMBL28215

Clc1ccc(-c2ccc(Cl)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.73
LMNA P02545 2/20 0.73
CYP2A6 P11509 1/20 0.73
AHR P35869 2/20 0.61
ALOX5 P09917 1/20 0.55
IDO1 P14902 2/20 0.50
MAOB P27338 1/20 0.50
TSHR P16473 2/20 0.47
KIF11 P52732 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MAPK1 P28482 2/20 0.45
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.45
HIF1A Q16665 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NOTUM Q6P988 1/20 0.43
POLB P06746 1/20 0.43
PTPN11 Q06124 1/20 0.43
CES2 O00748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11165087 1.00 CYP1A2 (0.73) CYP1A2LMNACYP2A6AHRALOX5
SCHEMBL3952742 1.00 CYP1A2 (0.73) CYP1A2LMNACYP2A6AHRALOX5
SCHEMBL25437316 0.96 CYP1A2 (0.69) CYP1A2LMNACYP2A6AHRALOX5
Hydrogen Sulfide SCHEMBL10394839 0.96 CYP1A2 (0.69) CYP1A2LMNACYP2A6AHRALOX5
Ethyne SCHEMBL29216096 0.92 CYP1A2 (0.65) CYP1A2LMNACYP2A6AHRALOX5
SCHEMBL9160072 0.89 AHR (0.68) CYP1A2LMNACYP2A6AHRALOX5
SCHEMBL28631682 0.89 CYP1A2 (0.61) CYP1A2LMNACYP2A6AHRALOX5
Methyl Alcohol SCHEMBL28374011 0.89 CYP1A2 (0.61) CYP1A2LMNACYP2A6AHRALOX5
Methylene Chloride SCHEMBL22344179 0.89 CYP1A2 (0.61) CYP1A2LMNACYP2A6AHRALOX5
SCHEMBL4454036 0.86 CYP1A2 (1.00) CYP1A2LMNACYP2A6AHRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 950 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881907-A1 METHOD FOR DECHLORINATION OF ONE OR MORE AROMATIC ORGANOCHLORINE COMPOUND(S) CONTAINED IN AN OIL OR FORMING SAID OIL - ASSOCIATED ELECTRICAL/ELECTRONIC DEVICE AND INSTALLATION Université de Lille (FR) 2021-09-22 EP claimed
EP-3774726-A1 PROCESS FOR PRODUCING 4,4`-DICHLORODIPHENYL SULFOXIDE BASF SE (DE) 2021-02-17 EP claimed
WO-2020161228-A1 PROCESS FOR PRODUCING 4,4`-DICHLORODIPHENYL SULFOXIDE BASF SE (DE) 2020-08-13 WO claimed
CN-111056911-A Method for preparing 4, 4' -dichlorobiphenyl 广东石油化工学院 2020-04-24 CN claimed
CN-111039848-A Preparation method of 4, 4' -dicarbazolylbiphenyl 广东石油化工学院 2020-04-21 CN claimed
EP-3433300-A1 DESALINATION OF POLYARYL ETHERS BY MEANS OF MELT EXTRACTION BASF SE (DE) 2019-01-30 EP claimed
WO-2016050798-A1 (CO)POLYMERS INCLUDING CYCLIC DIAMIDES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-04-07 WO claimed
US-8759458-B2 Method for producing poly(arylene ether) block copolymers BASF SE (DE) 2014-06-24 US claimed
WO-2011067649-A2 PROCESS FOR THE PRODUCTION OF A SULFONE MONOMER BANDODKAR HEMANT RATANAKAR (IN) 2011-06-09 WO claimed
EP-0968739-B1 Method for decomposing halogenated aliphatic and aromatic compounds CANON KK (JP) 2010-06-16 EP claimed
US-4952665-A Process for production of aromatic polyethers with alkali metal carbonate/bicarbonate/fluoride cocatalyst MITSUBISHI GAS CHEMICAL COMPANY, LTD. (JP) 1990-08-28 US claimed
EP-0306051-A1 Process for production of aromatic polyethers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-03-08 EP claimed
US-4806485-A PHOTOOXYGENATION COOPERATIVE INSTITUTE FOR RESEARCH IN ENVIRONMENTAL SCIENCES UNIVERS. OF COLORADO (US) 1989-02-21 US claimed
US-4686239-A WITHIN PORES OF THERMOPLASTIC POWDER; MORTON THIOKOL, INC. (US) 1987-08-11 US claimed
US-4663359-A POROUS THERMOPLASTIC, NON-DUSTING MORTON THIOKOL, INC. (US) 1987-05-05 US claimed
US-4661528-A HIGH CONCENTRATION, POROUS THERMOPLASTIC POWDER, NON-DUSTING AND FREE-FLOWING MORTON THIOKOL, INC. (US) 1987-04-28 US claimed
US-4576688-A Production of poly(p-phenylene) from 4,4'-dihalobiphenyl and lithium using ultrasonic waves CELANESE CORPORATION (US) 1986-03-18 US claimed
EP-0079144-B1 PROCESS FOR PRODUCING AROMATIC SULFIDE POLYMERS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-01-29 EP claimed
US-4451640-A Process for producing aromatic sulfide polymer KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-05-29 US claimed
EP-0079144-A1 Process for producing aromatic sulfide polymers KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1983-05-18 EP claimed