Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132140 | 0.89 | GRM5 (0.66) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL30707880 | 0.89 | GRM5 (0.66) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL25490057 | 0.86 | GRM5 (0.54) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL29994376 | 0.83 | GRM5 (0.56) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL7601866 | 0.83 | GRM5 (0.56) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL4267103 | 0.83 | CA12 (0.63) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL28397792 | 0.82 | CA1 (0.58) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL8207581 | 0.82 | GRM5 (0.54) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL27916593 | 0.82 | GRM5 (0.54) | GRM5CA1CA2CA9CA12 | |
| SCHEMBL24434459 | 0.82 | GRM5 (0.54) | GRM5CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107963996-B | Method for preparing 3-trifluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-108069918-B | Method for preparing 3-difluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-108069918-A | Method for preparing 3-difluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2018-05-25 | — | — | CN | disclosed |
| CN-107963996-A | Method for preparing 3-trifluoromethyl isoxazole compound by one-pot method | 江西师范大学 | 2018-04-27 | — | — | CN | disclosed |