Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28215437

N.O=C(CCI)OCc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
MAPK1 P28482 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
TDP1 Q9NUW8 3/20 0.52
KMT2A Q03164 2/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A3 Q01959 1/20 0.52
LMNA P02545 3/20 0.50
NOTUM Q6P988 1/20 0.50
HCAR2 Q8TDS4 1/20 0.47
MEN1 O00255 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
CDC25B P30305 1/20 0.46
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9840777 0.98 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
Ammonia Solution, Strong SCHEMBL27465058 0.89 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL7696360 0.87 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL1177836 0.86 ALDH1A1 (0.73) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL21121060 0.86 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL3727214 0.85 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL8892351 0.85 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL10839078 0.84 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL11842148 0.84 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1TDP1KMT2A
SCHEMBL22017059 0.83 MEN1 (0.53) ALDH1A1MAPK1L3MBTL1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108047268-A A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application 中国科学技术大学 2018-05-18 CN claimed
CN-108047268-A A kind of miscellaneous two ring of -5- alkyl [3.3.3] the hendecane class compound of 1- azepines -5- germanium, synthetic method and application 中国科学技术大学 2018-05-18 CN disclosed