Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14338705 | 0.77 | PPARD (0.44) | TSHRALDH1A1PPARDLMNATDP1 | |
| SCHEMBL2028174 | 0.77 | TSHR (0.46) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2235112 | 0.76 | CYP1A2 (0.52) | TSHRSMN1; SMN2ALDH1A1GAAPPARD | |
| SCHEMBL15951701 | 0.76 | CYP1A2 (0.52) | TSHRSMN1; SMN2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL29105537 | 0.75 | PPARD (0.44) | TSHRSMN1; SMN2ALDH1A1GAAPPARD | |
| SCHEMBL7212781 | 0.74 | TSHR (0.76) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11239793 | 0.73 | TSHR (0.44) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11203182 | 0.73 | TSHR (0.52) | TSHRALDH1A1PPARDL3MBTL1LMNA | |
| SCHEMBL21626322 | 0.73 | TSHR (0.46) | TSHRPKMSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL437266 | 0.72 | TSHR (0.85) | TSHRPKMSMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973818-A | A kind of preparation method of cremart | 江苏大学 | 2018-05-01 | — | — | CN | claimed |
| CN-107973818-A | A kind of preparation method of cremart | 江苏大学 | 2018-05-01 | — | — | CN | disclosed |