Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239793 | 0.84 | TSHR (0.44) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL14706209 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| Phosphoric Acid SCHEMBL27674703 | 0.77 | TSHR (0.55) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL56403 | 0.76 | TSHR (0.63) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10595435 | 0.75 | TSHR (0.59) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8816347 | 0.75 | TSHR (0.58) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL10895521 | 0.75 | ALDH1A1 (0.44) | TSHRSMN1; SMN2ALDH1A1LMNACYP3A4 | |
| Ammonia Solution, Strong SCHEMBL29207431 | 0.74 | TSHR (0.61) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28545578 | 0.74 | TSHR (0.61) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9062792 | 0.73 | TSHR (0.56) | TSHRPKMSMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11746111-B2 | Siderophore conjugated pyrazolidinones, and analogues thereof | YALE UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746111-B2 | Siderophore conjugated pyrazolidinones, and analogues thereof | YALE UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| US-11746111-B2 | Siderophore conjugated pyrazolidinones, and analogues thereof | YALE UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| WO-2020018929-A1 | SIDEROPHORE CONJUGATED PYRAZOLIDINONES, AND ANALOGUES THEREOF | YALE UNIVERSITY (US) | 2020-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11746111-B2 | Siderophore conjugated pyrazolidinones, and analogues thereof | SLC40A1, HAMP, SLC39A11 | TSHR 1286/4885PKM 1609/4885SMN1; SMN2 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.