Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.61 |
| ▸ | LPL | P06858 | 11/20 | 0.61 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23071684 | 0.87 | LIPG (0.70) | LIPGLPLANPEPLAP3DGAT1 | |
| SCHEMBL20904633 | 0.86 | LIPG (0.57) | LIPGLPLF11 | |
| SCHEMBL31298117 | 0.85 | LIPG (0.53) | LIPGLPLDGAT1F11 | |
| SCHEMBL14165539 | 0.84 | LIPG (0.65) | LIPGLPLANPEPLAP3DGAT1 | |
| SCHEMBL18332737 | 0.83 | LIPG (0.69) | LIPGLPLANPEPLAP3DGAT1 | |
| SCHEMBL16768507 | 0.83 | LIPG (0.78) | LIPGLPLANPEPLAP3DGAT1 | |
| SCHEMBL1284463 | 0.81 | LIPG (0.63) | LIPGLPLDGAT1F11 | |
| SCHEMBL1331631 | 0.81 | LIPG (0.63) | LIPGLPLANPEPLAP3F11 | |
| SCHEMBL3039403 | 0.81 | LIPG (0.63) | LIPGLPLANPEPLAP3DGAT1 | |
| SCHEMBL20549868 | 0.80 | LIPG (0.58) | LIPGLPLANPEPLAP3DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069957-B | Prolyl hydroxylase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-108069957-A | Prolyl hydroxylase inhibitors and application thereof | 广东东阳光药业有限公司 | 2018-05-25 | — | — | CN | disclosed |