Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12407030 | 0.85 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL30024181 | 0.81 | KDM1A (0.53) | KMT2AMEN1KDM1ALMNAALDH1A1 | |
| SCHEMBL12678672 | 0.80 | EGFR (0.44) | KMT2AMEN1LMNAEPHX2SMN1; SMN2 | |
| SCHEMBL28215774 | 0.77 | KDM1A (0.59) | KDM1AALDH1A1 | |
| SCHEMBL488839 | 0.77 | CA1 (0.52) | KMT2AMEN1EPHX2SMN1; SMN2POLB | |
| SCHEMBL488233 | 0.76 | MEN1 (0.40) | KMT2AMEN1LMNAEPHX2ALDH1A1 | |
| SCHEMBL19025353 | 0.75 | KDM1A (0.63) | KMT2AKDM1ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5151273 | 0.75 | CD274 (0.63) | LMNAEPHX2SMN1; SMN2MAPTPOLB | |
| Hydrochloric Acid SCHEMBL11529235 | 0.75 | KMT2A (0.97) | KMT2AMEN1EPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL30024136 | 0.75 | PARP1 (0.49) | KDM1AEPHX2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922362-A | 1,3, 4-oxadiazole sulfonamide derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社钟根堂 | 2018-04-17 | — | — | CN | disclosed |