Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | CA12 | O43570 | 3/20 | 0.71 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.71 |
| ▸ | CA7 | P43166 | 3/20 | 0.71 |
| ▸ | CA9 | Q16790 | 3/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.64 |
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4-Dihydroxybenzoic Acid SCHEMBL3278615 | 0.94 | ALDH1A1 (0.80) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL93207 | 0.93 | MEN1 (0.69) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL29517975 | 0.93 | MEN1 (0.69) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL30668331 | 0.91 | ALDH1A1 (0.68) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL1174964 | 0.91 | ALDH1A1 (0.68) | ALDH1A1CA12CA1CA2CA7 | |
| Aminosalicylic Acid SCHEMBL28161022 | 0.91 | ALDH1A1 (0.65) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL22939382 | 0.89 | CA12 (0.60) | ALDH1A1CA12CA1CA2CA7 | |
| 2,4-Dihydroxybenzophenone SCHEMBL10897776 | 0.88 | MEN1 (0.86) | ALDH1A1CA12CA1CA2CA7 | |
| 2,4-Dihydroxybenzoic Acid SCHEMBL28147403 | 0.87 | ALDH1A1 (0.95) | ALDH1A1CA12CA1CA2CA7 | |
| 2,4-Dihydroxybenzophenone SCHEMBL10822811 | 0.86 | MEN1 (0.89) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105047540-B | Anti-reflecting layer and method | 台湾积体电路制造股份有限公司 | 2018-05-25 | — | — | CN | disclosed |