SCHEMBL28215985

SCHEMBL28215985

C=C(C)C(=O)OC(C)C(C)N(C(C)C)C(C)C.C=C(C)C(=O)OCC1CO1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
TSHR P16473 2/20 0.36
CYP3A4 P08684 2/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28215410 0.89 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4TP53
Isobutane SCHEMBL11145297 0.82 ALDH1A1 (0.89) ALDH1A1TSHRCYP3A4TP53CYP2D6
SCHEMBL27467603 0.80 TSHR (0.39) ALDH1A1TSHR
SCHEMBL15617 0.80 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4TP53CYP2D6
SCHEMBL2048901 0.80 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4TP53CYP2D6
SCHEMBL5098171 0.80 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4TP53CYP2D6
SCHEMBL5098181 0.80 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4TP53CYP2D6
SCHEMBL9751485 0.79 ALDH1A1 (0.96) ALDH1A1TSHRCYP3A4TP53CYP2D6
Bromide SCHEMBL18420123 0.79 ALDH1A1 (0.96) ALDH1A1TSHRCYP3A4TP53CYP2D6
SCHEMBL20496120 0.79 ALDH1A1 (0.96) ALDH1A1TSHRCYP3A4TP53CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105273207-B Polycation inclusion compound, preparation method and the usage 中国科学院上海药物研究所 2018-04-17 CN claimed