Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491219 | 0.94 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL278688 | 0.78 | TSHR (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL56531 | 0.78 | TSHR (0.37) | TSHRTHRBALDH1A1 | |
| SCHEMBL148579 | 0.76 | TSHR (0.58) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL164047 | 0.76 | THRB (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL8452794 | 0.74 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Benzene SCHEMBL28145673 | 0.74 | THRB (0.65) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Ammonia Solution, Strong SCHEMBL28190576 | 0.74 | THRB (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28189930 | 0.74 | THRB (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Hydrochloric Acid SCHEMBL14976774 | 0.74 | TSHR (0.56) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922739-A | Copolymers comprising polysiloxane macromonomer units, process for their preparation and their use in coating compositions and polymeric moulding compounds | 毕克化学有限公司 | 2018-04-17 | — | — | CN | disclosed |