Ethylene Glycol

Ethylene Glycol

SCHEMBL28216321

CC(=O)CCC(=O)OC(C)=O.OCCO

nearest known ligand 0.48

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TSHR P16473 2/20 0.41
LMNA P02545 1/20 0.40
SLC15A2 Q16348 1/20 0.40
TDP1 Q9NUW8 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
MAPT P10636 1/20 0.31
ACHE P22303 1/20 0.30
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5273856 0.93 ALDH1A1 (0.56) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL27851638 0.90 ALDH1A1 (0.53) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL27970775 0.90 ALDH1A1 (0.53) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL11591970 0.90 ALDH1A1 (0.53) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL28749707 0.88 ALDH1A1 (0.50) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL35205 0.84 ALDH1A1 (0.56) ALDH1A1TSHRLMNASLC15A2TDP1
Ethylene Glycol SCHEMBL27494935 0.84 EGLN1 (0.45) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL2124442 0.82
SCHEMBL10776617 0.82 ALDH1A1 (0.53) ALDH1A1TSHRLMNASLC15A2TDP1
SCHEMBL9861711 0.82 ALDH1A1 (0.53) ALDH1A1TSHRLMNASLC15A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104685046-B Diacetyl propionic acid diol ester is as the coupling agent in cleaning agent 陶氏环球技术有限责任公司 2018-05-22 CN disclosed