Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.59 |
| ▸ | MIF | P14174 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 12/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11963957 | 1.00 | PLA2G7 (0.59) | PLA2G7MIFFAAHNPC1RAB9A | |
| SCHEMBL29208564 | 0.86 | MIF (0.61) | PLA2G7MIFFAAHNPC1RAB9A | |
| SCHEMBL11963956 | 0.86 | MIF (0.61) | PLA2G7MIFFAAHNPC1RAB9A | |
| SCHEMBL28360449 | 0.84 | MIF (0.55) | MIFNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28401929 | 0.83 | MIF (0.76) | PLA2G7MIFFAAHNPC1RAB9A | |
| SCHEMBL11963970 | 0.83 | MIF (0.76) | PLA2G7MIFFAAHNPC1RAB9A | |
| SCHEMBL28360431 | 0.83 | MIF (0.54) | PLA2G7MIFMEN1KMT2A | |
| SCHEMBL28364014 | 0.82 | NPC1 (0.50) | PLA2G7MIFNPC1RAB9AMEN1 | |
| SCHEMBL10628173 | 0.82 | PLA2G7 (0.51) | PLA2G7MIFFAAHNPC1RAB9A | |
| SCHEMBL13044360 | 0.81 | KMT2A (0.53) | MIFFAAHNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669046-B | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-110669046-A | Polysubstituted tetrahydro-gamma-carboline derivative with multiple chiral centers and preparation method of stereo diversity of polysubstituted tetrahydro-gamma-carboline derivative | 武汉大学 | 2020-01-10 | — | — | CN | disclosed |
| CN-108129387-A | A kind of preparation method for synthesizing 2- azabicyclics [4.1.0] heptane -1- carboxylic acid hydrochlorides | 南京药石科技股份有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-108026026-A | Beta-amino acids and analog and its application as the β-substituted of chemotherapeutics | 夸德里加生物科学公司 | 2018-05-11 | — | — | CN | disclosed |