Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.77 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683803 | 0.91 | PTGS1 (0.68) | PTGS1P2RX1HDAC3HDAC8HDAC6 | |
| SCHEMBL678064 | 0.87 | PTGS1 (0.77) | PTGS1P2RX1HDAC3HDAC8HDAC6 | |
| SCHEMBL678654 | 0.87 | PTGS1 (1.00) | PTGS1HDAC3HDAC8HDAC6MEN1 | |
| SCHEMBL11307930 | 0.86 | PTGS1 (0.76) | PTGS1P2RX1MEN1LMNAKMT2A | |
| SCHEMBL28329635 | 0.85 | P2RX1 (0.64) | PTGS1P2RX1HDAC3HDAC8HDAC6 | |
| SCHEMBL19638212 | 0.84 | P2RX1 (0.71) | PTGS1P2RX1HDAC3HDAC8HDAC6 | |
| SCHEMBL11799771 | 0.84 | P2RX1 (0.71) | P2RX1HDAC3HDAC8HDAC6MEN1 | |
| SCHEMBL23447713 | 0.83 | P2RX1 (1.00) | P2RX1HDAC3HDAC8HDAC6LMNA | |
| SCHEMBL2914683 | 0.83 | P2RX1 (0.74) | P2RX1HDAC3HDAC8HDAC6LMNA | |
| SCHEMBL7588013 | 0.82 | PTGS1 (0.60) | PTGS1P2RX1HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084096-A | 2- phenyl pyrimidine classes compound, preparation method and medical usage | 中国药科大学 | 2018-05-29 | — | — | CN | disclosed |