Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 7/20 | 0.64 |
| ▸ | JUN | P05412 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914683 | 0.88 | P2RX1 (0.74) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL548237 | 0.85 | PTGS1 (0.77) | P2RX1PTGS1HDAC3HDAC8HDAC6 | |
| SCHEMBL28217080 | 0.85 | PTGS1 (0.77) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL549108 | 0.84 | MAPT (0.73) | P2RX1PTGS1MAPT | |
| SCHEMBL678064 | 0.82 | PTGS1 (0.77) | P2RX1PTGS1HDAC3HDAC8HDAC6 | |
| SCHEMBL3298253 | 0.82 | PKM (0.52) | PTGS1 | |
| SCHEMBL22387581 | 0.81 | LMNA (0.67) | P2RX1PTGS1HDAC3HDAC8HDAC6 | |
| SCHEMBL30554615 | 0.80 | P2RX1 (0.65) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL3246188 | 0.80 | P2RX1 (0.65) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL23447713 | 0.78 | P2RX1 (1.00) | P2RX1JUNNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110358086-A | A kind of fluorine-containing high transparency polyimides of amide containing and preparation method thereof | 株洲时代新材料科技股份有限公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-110256278-A | A kind of amide containing fluorinated diamine monomer being used to prepare high transparency polyimides and preparation method thereof, application | 株洲时代新材料科技股份有限公司 | 2019-09-20 | — | — | CN | disclosed |