Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28210090 | 0.92 | MMP8 (0.53) | MEN1NPC1KMT2AMMP8PIN1 | |
| SCHEMBL28209523 | 0.88 | MEN1 (0.47) | MEN1NPC1KMT2AMMP8PIN1 | |
| SCHEMBL22425310 | 0.80 | MMP8 (0.46) | MMP8PIN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9667155 | 0.80 | MEN1 (0.50) | MEN1NPC1KMT2AMMP8PIN1 | |
| SCHEMBL2746977 | 0.79 | PTGS1 (0.56) | MEN1NPC1KMT2AMMP8PTGS1 | |
| SCHEMBL14921012 | 0.78 | MMP8 (0.51) | MEN1NPC1KMT2AMMP8PIN1 | |
| SCHEMBL25923543 | 0.78 | MMP8 (0.51) | MEN1NPC1KMT2AMMP8PIN1 | |
| SCHEMBL20543782 | 0.78 | MMP8 (0.51) | MEN1NPC1KMT2AMMP8PIN1 | |
| SCHEMBL5907869 | 0.78 | MMP8 (0.51) | MEN1NPC1KMT2AMMP8PIN1 | |
| SCHEMBL25602723 | 0.78 | MMP8 (0.51) | MEN1NPC1KMT2AMMP8PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107986978-A | A kind of preparation method of cardiotonic agents Sha Kubi song intermediates | 临沂齐泽医药技术有限公司 | 2018-05-04 | — | — | CN | disclosed |