SCHEMBL28217427

SCHEMBL28217427

CC(=S)Cc1cccc(F)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.47
MIF P14174 1/20 0.46
IDO1 P14902 2/20 0.46
AGXT P21549 2/20 0.46
MAOB P27338 5/20 0.44
MAOA P21397 1/20 0.41
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PTPN7 P35236 2/20 0.40
DUSP3 P51452 2/20 0.40
KCNQ2 O43526 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3025521 0.83 TAAR1 (0.50) TAAR1MIFIDO1AGXTMAOB
SCHEMBL29846287 0.80 TAAR1 (0.52) TAAR1MIFIDO1AGXTMAOB
SCHEMBL6896362 0.80 TAAR1 (0.52) TAAR1MIFIDO1AGXTMAOB
SCHEMBL27791783 0.80 TAAR1 (0.52) TAAR1MIFIDO1AGXTMAOB
SCHEMBL1426756 0.80 MAOB (0.51) TAAR1IDO1AGXTMAOBMAOA
SCHEMBL14884689 0.80 TAAR1 (0.47) TAAR1MIFIDO1AGXTMAOB
SCHEMBL4659432 0.77 IDO1 (0.47) TAAR1IDO1AGXTMAOBMAOA
SCHEMBL27383159 0.76 TAAR1 (0.47) TAAR1IDO1AGXTMAOB
SCHEMBL4872149 0.76 PTPN7 (0.53) TAAR1ALDH1A1PTPN7DUSP3
SCHEMBL16962475 0.76 TAAR1 (0.43) TAAR1MIFIDO1AGXTMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105175345-B A kind of method for preparing Rosuvastatin intermediate 上海应用技术学院 2018-05-22 CN disclosed