Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Naphthalene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL3796240 | 0.94 | CYP2A6 (0.57) | CYP2A6ALOX12CA2CA4CA5A | |
| Naphthalene SCHEMBL19062554 | 0.94 | CYP2A6 (0.57) | CYP2A6ALOX12CA2CA4CA5A | |
| Naphthalene SCHEMBL30423233 | 0.94 | CYP2A6 (0.57) | CYP2A6ALOX12CA2CA4CA5A | |
| Naphthalene SCHEMBL30445823 | 0.94 | CYP2A6 (0.57) | CYP2A6ALOX12CA2CA4CA5A | |
| Naphthalene SCHEMBL1680172 | 0.94 | CYP2A6 (0.57) | CYP2A6ALOX12CA2CA4CA5A | |
| Naphthalene SCHEMBL28848051 | 0.90 | CYP2A6 (0.53) | CYP2A6ALOX12CA2CA4CA5A | |
| Naphthalene SCHEMBL28905256 | 0.88 | CYP2A6 (0.50) | CYP2A6ALOX12CA2CA4CA5A | |
| Naphthalene SCHEMBL194159 | 0.83 | CYP2A6 (0.73) | CYP2A6ALOX12CA2L3MBTL1ALOX15 | |
| Naphthalene SCHEMBL8366099 | 0.83 | CYP2A6 (0.73) | CYP2A6ALOX12CA2L3MBTL1ALOX15 | |
| Anthracene SCHEMBL27692909 | 0.82 | PTPN1 (0.47) | ALOX12CA2CA4CA5APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108219648-A | A kind of T8 straight tubes diffusion powder coating and its preparation process | 浙江江山三友电子有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-213699611-U | Water-reducing agent anti-caking agitating unit | 河北方霖环保科技有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-108219648-A | A kind of T8 straight tubes diffusion powder coating and its preparation process | 浙江江山三友电子有限公司 | 2018-06-29 | — | — | CN | disclosed |