Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153638 | 0.96 | TSHR (0.46) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| Fluoride SCHEMBL27639893 | 0.92 | TSHR (0.43) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL702940 | 0.92 | TSHR (0.43) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL10423271 | 0.92 | TSHR (0.43) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2140790 | 0.92 | TSHR (0.43) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL706848 | 0.92 | TSHR (0.43) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| Bromide SCHEMBL31547794 | 0.92 | TSHR (0.43) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL704491 | 0.92 | TSHR (0.43) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL16497147 | 0.89 | TSHR (0.47) | TSHRLMNAALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL10415307 | 0.89 | TSHR (0.40) | TSHRLMNAALDH1A1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073894-B | Solidification compound | 积水富乐株式会社 | 2018-06-08 | — | — | CN | disclosed |