Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.52 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31447593 | 0.87 | — | — | |
| SCHEMBL364517 | 0.87 | — | — | |
| Formaldehyde SCHEMBL28284792 | 0.85 | TRIM24 (0.47) | TRIM24TRIM33NFE2L2S1PR4SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28133281 | 0.85 | — | — | |
| Bromide SCHEMBL1337860 | 0.85 | — | — | |
| Formic Acid Methyl Ester SCHEMBL28284857 | 0.83 | TRIM24 (0.47) | TRIM24TRIM33NFE2L2S1PR4 | |
| Cyanide SCHEMBL28200594 | 0.81 | TRIM24 (0.42) | TRIM24TRIM33NFE2L2S1PR4SMN1; SMN2 | |
| Formic Acid SCHEMBL28210582 | 0.79 | SMN1; SMN2 (0.48) | TRIM24TRIM33NFE2L2SMN1; SMN2HTT | |
| Formic Acid SCHEMBL28014997 | 0.76 | TRIM24 (0.52) | TRIM24TRIM33SMN1; SMN2HTTALDH1A1 | |
| Formic Acid SCHEMBL27951317 | 0.76 | TRIM24 (0.47) | TRIM24TRIM33NFE2L2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110312724-A | SUBSTITUTED THIAZOLO-PYRIDINE COMPOUNDS AS MALT1 INHIBITORS | 陆品有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110214136-A | Pyrazole derivatives as MALT1 inhibitor | 詹森药业有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-106458956-B | The heterocycle sulfone that heteroaryl replaces | 格吕伦塔尔有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-105189461-B | The dibasic 1- acyl groups -4- amino -1,2,3,4- tetrahydroquinoline derivatives of 2,3- and their purposes as bromine domain inhibitor | 葛兰素史克知识产权第二有限公司 | 2018-05-15 | — | — | CN | disclosed |