Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364517 | 0.93 | — | — | |
| SCHEMBL31447593 | 0.93 | — | — | |
| Bromide SCHEMBL1337860 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL28133281 | 0.91 | — | — | |
| Cyanide SCHEMBL28200594 | 0.86 | TRIM24 (0.42) | TRIM24TRIM33S1PR4NFE2L2SMN1; SMN2 | |
| Formic Acid SCHEMBL28217690 | 0.85 | TRIM24 (0.52) | TRIM24TRIM33S1PR4NFE2L2SMN1; SMN2 | |
| Formic Acid Methyl Ester SCHEMBL28284857 | 0.81 | TRIM24 (0.47) | TRIM24TRIM33S1PR4NFE2L2HSD11B1 | |
| Formaldehyde SCHEMBL27551738 | 0.76 | SMN1; SMN2 (0.48) | NFE2L2SMN1; SMN2ALDH1A1HTTLMNA | |
| Formaldehyde SCHEMBL29049926 | 0.73 | NFE2L2 (0.41) | NFE2L2LMNAHSD11B1 | |
| Formaldehyde SCHEMBL28529254 | 0.73 | TRIM24 (0.47) | TRIM24TRIM33NFE2L2HTTCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458956-B | The heterocycle sulfone that heteroaryl replaces | 格吕伦塔尔有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109563057-A | Sulfonamide compounds or its salt | 大鹏药品工业株式会社 | 2019-04-02 | — | — | CN | disclosed |