Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388321 | 0.84 | KDM4E (0.49) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL6510910 | 0.84 | PIK3CD (0.53) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL3442682 | 0.78 | ELANE (0.45) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL6686583 | 0.77 | PIK3CD (0.40) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL29528497 | 0.76 | NPC1 (0.56) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL9352365 | 0.74 | PIK3CD (0.60) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL13833704 | 0.73 | MAPT (0.60) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL13822671 | 0.73 | MAPT (0.45) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL15398164 | 0.72 | MAPT (0.63) | PIK3CDPIK3CBMAPTALDH1A1HPGD | |
| SCHEMBL21888585 | 0.72 | NPC1 (0.51) | MAPTALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104244944-B | For treating the compound of spinal muscular atrophy | PTC医疗公司 | 2018-06-08 | — | — | CN | disclosed |