Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | ILK | Q13418 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3442682 | 0.83 | ELANE (0.45) | PIK3CDPIK3CBILKMAPTHPGD | |
| SCHEMBL28218224 | 0.77 | PIK3CD (0.47) | PIK3CDPIK3CBILKMAPTHPGD | |
| SCHEMBL6510910 | 0.75 | PIK3CD (0.53) | PIK3CDPIK3CBMAPTHPGDALDH1A1 | |
| SCHEMBL28388321 | 0.75 | KDM4E (0.49) | PIK3CDPIK3CBILKMAPTHPGD | |
| SCHEMBL4504988 | 0.73 | PIK3CD (0.61) | PIK3CDPIK3CBMAPTALDH1A1POLB | |
| SCHEMBL29405604 | 0.71 | ALDH1A1 (0.47) | PIK3CDPIK3CBMAPTHPGDALDH1A1 | |
| SCHEMBL29462435 | 0.70 | PAX8 (0.37) | PIK3CDPIK3CBIRAK4MAPTHPGD | |
| SCHEMBL20021603 | 0.69 | ALDH1A1 (0.48) | MAPTHPGDALDH1A1GAAPOLB | |
| SCHEMBL30914645 | 0.68 | ALDH1A1 (0.55) | MAPTHPGDALDH1A1GAATHRB | |
| SCHEMBL29249860 | 0.68 | ALDH1A1 (0.55) | MAPTHPGDALDH1A1GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483262-A1 | COUMARINES USEFUL AS BIOMARKERS | Novartis AG (CH) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074519-A1 | COUMARINES USEFUL AS BIOMARKERS | NOVARTIS AG (CH) | 2003-09-12 | — | — | WO | disclosed |