Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7289137 | 0.93 | KMT2A (0.60) | KMT2ASMN1; SMN2EPHX2MEN1HTT | |
| SCHEMBL3505235 | 0.86 | KMT2A (0.69) | KMT2ASMN1; SMN2EPHX2MEN1HDAC3 | |
| SCHEMBL31658991 | 0.85 | KMT2A (0.83) | KMT2ASMN1; SMN2EPHX2MEN1HDAC3 | |
| SCHEMBL9341104 | 0.85 | KMT2A (0.83) | KMT2ASMN1; SMN2EPHX2MEN1HDAC3 | |
| Hydrochloric Acid SCHEMBL5617815 | 0.84 | KMT2A (0.67) | KMT2ASMN1; SMN2EPHX2MEN1HDAC3 | |
| SCHEMBL1503134 | 0.83 | KMT2A (0.65) | KMT2ASMN1; SMN2EPHX2MEN1HTT | |
| SCHEMBL28244458 | 0.83 | KMT2A (0.65) | KMT2ASMN1; SMN2EPHX2MEN1HTT | |
| SCHEMBL18912555 | 0.83 | SMN1; SMN2 (0.74) | KMT2ASMN1; SMN2EPHX2MEN1HDAC3 | |
| SCHEMBL109657 | 0.82 | HDAC3 (0.61) | KMT2ASMN1; SMN2EPHX2HTTHDAC3 | |
| SCHEMBL28131851 | 0.82 | HDAC3 (0.61) | KMT2ASMN1; SMN2EPHX2HTTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026072-A | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2018-05-11 | — | — | CN | disclosed |