Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 1.00 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | CCR1 | P32246 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353598 | 1.00 | TRPV4 (1.00) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL5004499 | 1.00 | TRPV4 (1.00) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL5007988 | 1.00 | TRPV4 (1.00) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL4971055 | 0.97 | TRPV4 (0.94) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL5007170 | 0.94 | TRPV4 (0.89) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL5004275 | 0.93 | TRPV4 (0.87) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL5007926 | 0.92 | TRPV4 (0.85) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL5007997 | 0.91 | TRPV4 (0.84) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL4993946 | 0.91 | TRPV4 (0.84) | TRPV4TAS1R3TAS1R1CCR1CTSK | |
| SCHEMBL5007250 | 0.91 | TRPV4 (0.83) | TRPV4TAS1R3TAS1R1CCR1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179425-A1 | Single Cell Encapsulation in Compartmentalized Hydrogel Coatings | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2025-06-05 | — | — | US | disclosed |
| CN-115317488-B | Application of GSK1016790A in preparation of medicine for treating or relieving diabetic enteropathy | 南华大学附属第一医院 | 2024-04-23 | — | — | CN | disclosed |
| CN-114569614-B | Application of TRPV4 agonist in preparation of medicines for treating and/or preventing male infertility | 南华大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115317488-A | Application of GSK1016790A in preparing medicine for treating or relieving diabetic enteropathy | 南华大学附属第一医院 | 2022-11-11 | — | — | CN | disclosed |
| CN-113082032-B | Novel application of TRPV4 agonist | 中山大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114569614-A | Application of TRPV4 agonist in preparation of medicines for treating and/or preventing male infertility | 南华大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113082032-A | Novel application of TRPV4 agonist | 中山大学 | 2021-07-09 | — | — | CN | disclosed |
| CN-111195253-A | Novel application of TRPV4 agonist GSK1016790A | 南华大学 | 2020-05-26 | — | — | CN | disclosed |
| CN-108186647-B | Medical application of compound | 中南大学湘雅二医院 | 2020-04-07 | — | — | CN | disclosed |
| CN-105524034-B | Preparation, pharmacological action and the application for treating cerebral ischemia of coumarin derivative | 北京大学 | 2018-08-17 | — | — | CN | disclosed |
| CN-105566269-B | Preparation, pharmacological action and the application for treating itch of coumarin derivative | 北京大学 | 2018-07-10 | — | — | CN | disclosed |