Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18920792 | 0.85 | KDM1A (0.56) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL11936118 | 0.78 | EPHX1 (0.48) | SMN1; SMN2EPHX1GAAALDH1A1POLB | |
| SCHEMBL25992753 | 0.78 | HRH3 (0.63) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL26620801 | 0.78 | KDM1A (0.49) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL5863541 | 0.76 | HRH3 (0.67) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL27010659 | 0.75 | KDM1A (0.47) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL8812183 | 0.74 | HRH3 (0.64) | PKMSMN1; SMN2MAPTEPHX1KDM4E | |
| SCHEMBL26620802 | 0.74 | KDM1A (0.46) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL662613 | 0.74 | KDM4E (0.59) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL11941155 | 0.70 | HRH3 (0.39) | KDM1ASMN1; SMN2KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108752236-A | SHIP1 conditioning agents and relative method | 阿奎诺克斯药物（加拿大）公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-105026375-B | SHIP1 modulators and methods related thereto | 阿奎诺克斯药物（加拿大）公司 | 2018-06-05 | — | — | CN | disclosed |