Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26620801 | 0.91 | KDM1A (0.49) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL27010659 | 0.88 | KDM1A (0.47) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL28218657 | 0.85 | KDM1A (0.47) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL25992753 | 0.84 | HRH3 (0.63) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL26620802 | 0.84 | KDM1A (0.46) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL5863541 | 0.82 | HRH3 (0.67) | KDM1AMAOAMAOBPKMSMN1; SMN2 | |
| SCHEMBL2798417 | 0.79 | KDM1A (0.58) | KDM1AMAOAMAOBEPHX1SSTR3 | |
| SCHEMBL2197651 | 0.79 | KDM1A (0.58) | KDM1AMAOAMAOBEPHX1SSTR3 | |
| SCHEMBL2197644 | 0.79 | KDM1A (0.58) | KDM1AMAOAMAOBEPHX1SSTR3 | |
| SCHEMBL2198525 | 0.79 | KDM1A (0.58) | KDM1AMAOAMAOBEPHX1SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271344-B1 | PROCESS FOR PREPARING AMINOTETRAHYDROPYRANS | FIS FABBRICA ITALIANA SINTETICI SPA (IT) | 2020-08-26 | — | — | EP | disclosed |
| US-10377732-B2 | Process for preparing aminotetrahydropyrans | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2019-08-13 | — | — | US | disclosed |
| US-20180290995-A1 | Process For Preparing Aminotetrahydropyrans | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2018-10-11 | — | — | US | disclosed |
| EP-3271344-A1 | PROCESS FOR PREPARING AMINOTETRAHYDROPYRANS | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2018-01-24 | — | — | EP | disclosed |
| WO-2017093209-A1 | PROCESS FOR PREPARING AMINOTETRAHYDROPYRANS | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2017-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377732-B2 | Process for preparing aminotetrahydropyrans | DPP4, DPP3, DPP9 | KDM1A 1344/4885MAOA 652/4885MAOB 903/4885 |
| US-20180290995-A1 | Process For Preparing Aminotetrahydropyrans | DPP4, DPP3, DPP9 | KDM1A 1344/4885MAOA 652/4885MAOB 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.