SCHEMBL28218875

SCHEMBL28218875

C=C=C(CCC)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
FFAR3 O14843 1/20 0.46
TSHR P16473 5/20 0.39
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
AKR1B1 P15121 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
GPR84 Q9NQS5 7/20 0.34
PPARG P37231 7/20 0.34
PPARD Q03181 7/20 0.34
PPARA Q07869 7/20 0.34
HDAC11 Q96DB2 5/20 0.34
PTPN1 P18031 3/20 0.34
ALDH1A1 P00352 2/20 0.34
TLR2 O60603 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28125469 0.85 AKR1B1 (0.52) TSHRAKR1B1GPR84PPARGPPARD
SCHEMBL28069612 0.79 HDAC3 (0.48) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL9641073 0.72
Butyric Acid SCHEMBL28967767 0.70
SCHEMBL11498147 0.69 HDAC3 (0.61) HDAC3HDAC1HDAC2HDAC8FFAR3
Malonic Acid SCHEMBL12399755 0.69 HDAC3 (0.81) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL3683839 0.69
Butyric Acid SCHEMBL28082071 0.69
Ethylene SCHEMBL27551619 0.69 HDAC3 (0.52) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL81438 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104812751-B Nitrogen-containing heterocyclic compounds for the control of plant diseases 拜尔农作物科学股份公司 2018-06-05 CN disclosed