SCHEMBL28069612

SCHEMBL28069612

CCCC(=C=O)CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC8 Q9BY41 2/20 0.48
FFAR3 O14843 1/20 0.48
TSHR P16473 5/20 0.40
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
AKR1B1 P15121 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
LDHA P00338 1/20 0.36
SRR Q9GZT4 1/20 0.36
GPR84 Q9NQS5 7/20 0.36
PPARG P37231 7/20 0.36
PPARD Q03181 7/20 0.36
PPARA Q07869 7/20 0.36
HDAC11 Q96DB2 5/20 0.36
PTPN1 P18031 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TLR2 O60603 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28633792 0.83 GPR84 (0.56) TSHRAKR1B1GPR84PPARGPPARD
SCHEMBL28218875 0.79 HDAC3 (0.46) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL10803582 0.79
SCHEMBL27992700 0.79 LDHA (0.50) FFAR3TSHRLDHASRRSLC22A6
SCHEMBL31303932 0.77 FFAR3 (0.50) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL27849313 0.76 GPR84 (0.58) TSHRAKR1B1GPR84PPARGPPARD
SCHEMBL7054258 0.74
SCHEMBL16335876 0.73 HDAC3 (0.44) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL11498147 0.71 HDAC3 (0.61) HDAC3HDAC1HDAC2HDAC8FFAR3
Malonic Acid SCHEMBL12399755 0.71 HDAC3 (0.81) HDAC3HDAC1HDAC2HDAC8FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271615-A Sulfur-containing polymer-based optical material with high light transmittance, high refraction and low dispersion and preparation method thereof 常州汉韦聚合物有限公司 2024-07-02 CN claimed
CN-118271615-A Sulfur-containing polymer-based optical material with high light transmittance, high refraction and low dispersion and preparation method thereof 常州汉韦聚合物有限公司 2024-07-02 CN disclosed
CN-105779517-B The method of diacylglycerol content during reduction enzyme process esterification deacidification WUHAN POLYTECHNIC UNIVERSITY (CN) 2019-10-29 CN disclosed
CN-105779517-A Method for reducing content of diglyceride in enzymic-method esterification deacidification process 丰益(上海)生物技术研发中心有限公司 2016-07-20 CN disclosed