SCHEMBL2821897

SCHEMBL2821897

NCCCC[C@H](N)C(=O)OC[C@H](N)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.68
RNPEP Q9H4A4 1/20 0.46
ARG2 P78540 4/20 0.43
ARG1 P05089 3/20 0.43
CPB2 Q96IY4 2/20 0.42
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39
NOS3 P29474 2/20 0.39
NOS1 P29475 2/20 0.39
NOS2 P35228 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
SLC1A5 Q15758 1/20 0.38
GNAI3 P08754 1/20 0.38
GNAO1 P09471 1/20 0.38
GNAI1 P63096 1/20 0.38
TLR2 O60603 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9780155 1.00 GSR (0.68) GSRRNPEPARG2ARG1CPB2
Lysine SCHEMBL15283763 0.98 GSR (0.71) GSRRNPEPARG2ARG1CPB2
SCHEMBL14486200 0.94 GSR (0.59) GSRRNPEPARG2ARG1CPB2
Alanine SCHEMBL4961214 0.93 GSR (0.59) GSRRNPEPARG2ARG1CPB2
Lysine SCHEMBL8199478 0.93 GSR (0.65) GSRRNPEPARG2ARG1CPB2
SCHEMBL7530109 0.89 GSR (0.54) GSRRNPEPARG2ARG1CPB2
SCHEMBL16225105 0.85 GSR (0.50) GSRRNPEPARG2ARG1NOS3
Leucine SCHEMBL7557530 0.85 GSR (0.50) GSRRNPEPARG2ARG1NOS3
SCHEMBL5174418 0.84 GSR (0.71) GSRRNPEPARG2ARG1CPB2
Lysine SCHEMBL20362357 0.82 GSR (1.00) GSRRNPEPARG2ARG1CPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195533-A Antibodies against sequence similarity family 19 member a5 and methods of use thereof 纽洛可科学有限公司 2021-07-30 CN claimed
CN-113039271-A Bispecific binding agents targeting syndecan-1 and fibroblast growth factor receptors 田边三菱制药株式会社 2021-06-25 CN claimed
CN-117535166-B Special acid-feeding dyford bacterium for ensiling of bromhidrosis and application of special acid-feeding dyford bacterium 云南省畜牧兽医科学院 2024-04-05 CN disclosed
CN-117535166-A Special acid-feeding dyford bacterium for ensiling of bromhidrosis and application of special acid-feeding dyford bacterium 云南省畜牧兽医科学院 2024-02-09 CN disclosed
US-20230133587-A1 Amino Acid Mediated Gene Delivery and Its Uses CHINESE INSTITUTE FOR BRAIN RESEARCH, BEIJING (CN) 2023-05-04 US disclosed
CN-113769061-A Anti-diarrhea hawthorn pills and preparation method thereof 柳春曦 2021-12-10 CN disclosed
CN-113195533-A Antibodies against sequence similarity family 19 member a5 and methods of use thereof 纽洛可科学有限公司 2021-07-30 CN disclosed
US-11028380-B2 CAS9-CAS9 fusion proteins UNIVERSITY OF MASSACHUSETTS (US) 2021-06-08 US disclosed
US-20190276810-A1 CAS9-CAS9 FUSION PROTEINS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2019-09-12 US disclosed
CN-109689099-A Composition for preventing or treating IL-8-related diseases 中外制药株式会社 2019-04-26 CN disclosed
CN-105002244-B A kind of culture medium and cultural method for crimping streptomycete fermentation production capreomycin 宁夏泰瑞制药股份有限公司 2018-04-20 CN disclosed
US-20160060648-A1 Transgenic Plants with Enhanced Agronomic Traits MONSANTO TECHNOLOGY LLC (US) 2016-03-03 US disclosed
US-20130145493-A1 Transgenic Plants with Enhanced Agronomic Traits MONSANTO TECHNOLOGY LLC 2013-06-06 US disclosed
EP-1355919-B1 MOLECULES WITH EXTENDED HALF-LIVES, COMPOSITIONS AND USES THEREOF MEDIMMUNE LLC (US) 2010-11-24 EP disclosed
CN-1826129-A Methods and compositions relating to isoleucine boroproline compounds POINT THERAPEUTICS INC (US) 2006-08-30 CN disclosed
WO-1994023030-A2 METHODS AND MATERIALS RELATING TO THE FUNCTIONAL DOMAINS OF DNA BINDING PROTEINS ARCH DEVELOPMENT CORPORATION (US) 1994-10-13 WO disclosed