Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219220 | 1.00 | LTA4H (0.49) | LTA4HKDM4EALDH1A1POLBHDAC1 | |
| SCHEMBL4591511 | 0.80 | LTA4H (0.55) | LTA4HKDM4EALDH1A1HDAC1JAK2 | |
| SCHEMBL5951343 | 0.80 | LTA4H (0.55) | LTA4HKDM4EALDH1A1HDAC1JAK2 | |
| SCHEMBL18516568 | 0.80 | LTA4H (0.55) | LTA4HALDH1A1POLBHDAC1JAK2 | |
| SCHEMBL14924455 | 0.80 | LTA4H (0.55) | LTA4HALDH1A1POLBHDAC1JAK2 | |
| SCHEMBL10288535 | 0.80 | LTA4H (0.55) | LTA4HPOLBHDAC1JAK2MCHR1 | |
| SCHEMBL5193010 | 0.80 | LTA4H (0.55) | LTA4HKDM4EALDH1A1HDAC1JAK2 | |
| SCHEMBL28626109 | 0.79 | LTA4H (0.54) | LTA4HHDAC1CHRM4JAK2KCNH2 | |
| SCHEMBL12073513 | 0.79 | LTA4H (0.54) | LTA4HALDH1A1HDAC1JAK2 | |
| SCHEMBL1911332 | 0.78 | LTA4H (0.60) | LTA4HALDH1A1HDAC1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137518-A | As 6 inhibitor of histone deacetylase 1,3,4- oxadiazole derivatives compound and include its pharmaceutical composition | 株式会社钟根堂 | 2018-06-08 | — | — | CN | disclosed |