Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITPR3 | Q14573 | 8/20 | 1.00 |
| ▸ | ITPR2 | Q14571 | 4/20 | 1.00 |
| ▸ | ITPR1 | Q14643 | 4/20 | 1.00 |
| ▸ | INPPL1 | O15357 | 1/20 | 1.00 |
| ▸ | AKT1 | P31749 | 1/20 | 1.00 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.90 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386031 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL9387400 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL19532798 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL9439431 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL382752 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL2905564 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| SCHEMBL9439795 | 1.00 | ITPR3 (1.00) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| Ionositol (1,3,4,5,6) P5 SCHEMBL406796 | 0.97 | ITPR3 (0.94) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| Ionositol (1,3,4,5,6) P5 SCHEMBL2710469 | 0.97 | ITPR3 (0.94) | ITPR3ITPR2ITPR1INPPL1AKT1 | |
| Ionositol (1,3,4,5,6) P5 SCHEMBL5159171 | 0.97 | ITPR3 (0.94) | ITPR3ITPR2ITPR1INPPL1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842488-B2 | Polynucleotides encoding a human 3-phosphoinositide- dependent protein kinase | MEDICAL RESEARCH COUNCIL (GB) | 2010-11-30 | — | — | US | claimed |
| US-20100093027-A1 | Enzyme | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2010-04-15 | — | — | US | claimed |
| US-7595148-B2 | Methods and compositions for modulating T lymphocytes | IRM LLC (BM) | 2009-09-29 | — | — | US | claimed |
| US-7344870-B2 | 3-phosphoinositide-dependent protein kinase | MEDICAL RESEARCH COUNCIL (GB) | 2008-03-18 | — | — | US | claimed |
| US-7205390-B2 | Antibody which activates protein kinase; drug screening | MEDICAL RESEARCH COUNCIL (GB) | 2007-04-17 | — | — | US | claimed |
| EP-0983363-B1 | PHOSPHATIDYL-3,4.5-TRIPHOSPHATE-DEPENDENT PROTEIN KINASE | MEDICAL RES COUNCIL (GB) | 2005-11-23 | — | — | EP | claimed |
| US-20050032185-A1 | Enzyme | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2005-02-10 | — | — | US | claimed |
| US-20040265790-A1 | Methods and compositions for modulating T lymphocytes | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2004-12-30 | — | — | US | claimed |
| WO-2004066926-A2 | METHODS AND COMPOSITIONS FOR MODULATING T LYMPHOCYTES | IRM LLC (BM) | 2004-08-12 | — | — | WO | claimed |
| US-6703215-B2 | DETECTING PREFERENTIAL ENZYME INHIBITOR; OBTAIN SUBSTRATE, INCUBATE WITH ENZYME MIXTURE, EXPOSE TO ENZYME INHIBITOR, MONITOR FOR DECREASE IN ENZYMATIC ACTIVITY | EUROSCREEN, S.A. (BE) | 2004-03-09 | — | — | US | claimed |
| US-20030108971-A1 | Enzyme | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2003-06-12 | — | — | US | claimed |
| US-20020106713-A1 | Inhibitors of the inositol polyphosphate 5-phosphatase SHIP2 molecule | OGEDA SA (BE) | 2002-08-08 | — | — | US | claimed |
| EP-1097713-A1 | Inhibitors of the inositol polyphosphate 5-phosphatase ship-2 molecule | Euroscreen S.A. (BE) | 2001-05-09 | — | — | EP | claimed |
| EP-0918990-A1 | AN ASSAY WHICH MEASURES PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE MASS AT HIGH SENSITIVITY | UNIVERSITY OF DUNDEE (GB) | 1999-06-02 | — | — | EP | claimed |
| WO-1997049990-A1 | AN ASSAY WHICH MEASURES PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE MASS AT HIGH SENSITIVITY | UNIVERSITY OF DUNDEE (GB) | 1997-12-31 | — | — | WO | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| US-20250189526-A1 | SIGNATURES AND DETERMINANTS FOR DIAGNOSING INFECTIONS AND METHODS OF USE THEREOF | MEMED DIAGNOSTICS LTD. (IL) | 2025-06-12 | — | — | US | disclosed |
| US-4988682-A | Antigrowth agents for cells, disruption of signals by cells | UNIVERSITY OF PITTSBURGH (US) | 1991-01-29 | — | — | US | disclosed |
| WO-1990008539-A1 | MYO-INOSITOL ANALOGS AND METHODS FOR THEIR USE | UNIVERSITY OF PITTSBURGH (US) | 1990-08-09 | — | — | WO | disclosed |
| US-4937390-A | Chemical intermediates, cell growth inhibitator in animals | UNIVERSITY OF PITTSBURGH (US) | 1990-06-26 | — | — | US | disclosed |