Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302959 | 0.76 | DNMT1 (0.42) | DNMT1KDM4ESMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22123582 | 0.74 | DNMT1 (0.41) | DNMT1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL26373760 | 0.72 | DNMT1 (0.42) | DNMT1KDM4E | |
| SCHEMBL12510370 | 0.72 | CYP1A2 (0.44) | DNMT1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27190359 | 0.72 | PIM1 (0.44) | DNMT1KDM4E | |
| SCHEMBL27256674 | 0.72 | KDR (0.51) | SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL20646852 | 0.69 | HTT (0.44) | DNMT1KDM4ESMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL3300004 | 0.69 | ALDH1A1 (0.47) | DNMT1SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL22124434 | 0.68 | SMN1; SMN2 (0.36) | DNMT1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL17232810 | 0.67 | BRD4 (0.38) | DNMT1KDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137600-A | Condensed pyrazole derivatives as kinase inhibitor | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |