Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL28071526 | 0.88 | GABRR1 (0.52) | GABRR1ALDH1A1TSHRSLC7A5TP53 | |
| Alanine SCHEMBL28071528 | 0.88 | GABRR1 (0.52) | GABRR1ALDH1A1TSHRSLC7A5TP53 | |
| Ethylenediamine SCHEMBL28098324 | 0.88 | GABRR1 (0.57) | GABRR1SLC7A5TP53GSRRNPEP | |
| Ethylenediamine SCHEMBL26086247 | 0.88 | GABRR1 (0.57) | GABRR1SLC7A5TP53GSRRNPEP | |
| Ethylenediamine SCHEMBL11706753 | 0.88 | GABRR1 (0.57) | GABRR1SLC7A5TP53GSRRNPEP | |
| Lactic Acid SCHEMBL27177897 | 0.86 | TP53 (0.61) | GABRR1ALDH1A1TSHRSLC7A5TP53 | |
| Lactic Acid SCHEMBL1831319 | 0.86 | TP53 (0.61) | GABRR1ALDH1A1TSHRSLC7A5TP53 | |
| Lactic Acid SCHEMBL22346344 | 0.86 | TP53 (0.61) | GABRR1ALDH1A1TSHRSLC7A5TP53 | |
| Methylmalonic Acid SCHEMBL5875088 | 0.86 | GABRR1 (0.50) | GABRR1ALDH1A1TSHRSLC7A5TP53 | |
| Ethylenediamine SCHEMBL27951423 | 0.85 | GABRR1 (0.55) | GABRR1SLC7A5TP53GSRRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552949-A | Method for synthesizing high-density low-freezing-point hydrocarbon component by biomass platform compound | 中国科学院广州能源研究所 | 2021-03-26 | — | — | CN | claimed |
| CN-112552949-B | Method for synthesizing high-density low-freezing-point hydrocarbon component by biomass platform compound | 中国科学院广州能源研究所 | 2022-10-28 | — | — | CN | disclosed |
| CN-112552949-A | Method for synthesizing high-density low-freezing-point hydrocarbon component by biomass platform compound | 中国科学院广州能源研究所 | 2021-03-26 | — | — | CN | disclosed |
| CN-108289848-A | Pharmaceutical compositions comprising potent inhibitors of URAT1 | 阿迪亚生命科学公司 | 2018-07-17 | — | — | CN | disclosed |