SCHEMBL28219802

SCHEMBL28219802

CC1=C(C)C(C)=C(C)[C]1C1C=C(c2ccccc2CN)c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.39
HTR2A P28223 1/20 0.33
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
PNMT P11086 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28860142 0.80 TAAR1 (0.39) HTR2A
SCHEMBL28860091 0.73 ALDH1A1 (0.37)
SCHEMBL28860141 0.70 IDO1 (0.36)
SCHEMBL3787333 0.64 DPP4 (0.73) DPP4HTR2ANOS3NOS1NOS2
SCHEMBL2482120 0.62 DPP4 (0.57) DPP4NOS3NOS1NOS2PNMT
SCHEMBL3805255 0.61 DPP4 (0.55) DPP4NOS3NOS1NOS2PNMT
SCHEMBL16814939 0.60 DPP4 (0.59) DPP4PNMT
SCHEMBL3790037 0.59 DPP4 (0.52) DPP4NOS3NOS1NOS2PNMT
SCHEMBL1038044 0.59 DPP4 (0.69) DPP4NOS3NOS1NOS2PNMT
SCHEMBL3788233 0.58 DPP4 (0.52) DPP4NOS3NOS1NOS2PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137729-A It is used to form the catalyst of multimodal polymer 埃克森美孚化学专利公司 2018-06-08 CN disclosed