Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL16585426 | 0.94 | TSHR (0.42) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL16585424 | 0.94 | TSHR (0.42) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL28212831 | 0.94 | CYP3A4 (0.46) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL27924348 | 0.87 | — | — | |
| L-Lactic Acid SCHEMBL27943644 | 0.87 | — | — | |
| L-Lactic Acid SCHEMBL28859165 | 0.87 | TP53 (0.50) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL37615 | 0.87 | — | — | |
| L-Lactic Acid SCHEMBL371442 | 0.87 | TP53 (0.50) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| Lactic Acid SCHEMBL30879622 | 0.87 | TP53 (0.55) | TSHRCYP3A4NFKB1NPSR1CA1 | |
| L-Lactic Acid SCHEMBL25270068 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106213416-B | For compound, composition and the method for bitter taste to be reduced or eliminated | 卓莫赛尔公司 | 2018-05-11 | — | — | CN | disclosed |