Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL28212831 | 0.92 | CYP3A4 (0.46) | TP53LMNACYP3A4TSHRNFKB1 | |
| Lactic Acid SCHEMBL8024518 | 0.89 | TP53 (0.69) | TP53LMNACYP3A4TSHRNFKB1 | |
| Lactic Acid SCHEMBL15544221 | 0.89 | TP53 (0.69) | TP53LMNACYP3A4TSHRNFKB1 | |
| Lactic Acid SCHEMBL264447 | 0.89 | TP53 (0.69) | TP53LMNACYP3A4TSHRNFKB1 | |
| Trichloroacetic Acid SCHEMBL27769982 | 0.88 | TP53 (0.42) | TP53LMNACYP3A4TSHRNFKB1 | |
| Lactic Acid SCHEMBL10320997 | 0.87 | TP53 (0.65) | TP53LMNACYP3A4TSHRNFKB1 | |
| L-Lactic Acid SCHEMBL16585426 | 0.87 | TSHR (0.42) | TP53LMNACYP3A4TSHRNFKB1 | |
| L-Lactic Acid SCHEMBL16585424 | 0.87 | TSHR (0.42) | TP53LMNACYP3A4TSHRNFKB1 | |
| L-Lactic Acid SCHEMBL28219862 | 0.87 | TSHR (0.42) | TP53LMNACYP3A4TSHRNFKB1 | |
| Lactic Acid SCHEMBL27636540 | 0.87 | TP53 (0.65) | TP53LMNACYP3A4TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021025-A1 | STRUCTURALLY DIVERSE, STABLE, AND RADIATION-PROTECTIVE PARTICLE MATRIX SUNSCREEN AND COSMETIC COMPOSITIONS AND RELATED METHODS | LCS ADVANCED SOLUTIONS LLC (US) | 2026-01-22 | — | — | US | disclosed |
| US-12453681-B2 | Structurally diverse, stable, and radiation-protective particle matrix sunscreen and cosmetic compositions and related methods | LCS Advanced Solutions, LLC (US) | 2025-10-28 | — | — | US | disclosed |
| US-20240358609-A1 | STRUCTURALLY DIVERSE, STABLE, AND RADIATION-PROTECTIVE PARTICLE MATRIX SUNSCREEN AND COSMETIC COMPOSITIONS AND RELATED METHODS | LCS Advanced Solutions, LLC | 2024-10-31 | — | — | US | disclosed |
| US-12059487-B2 | Structurally diverse, stable, and radiation-protective particle matrix sunscreen and cosmetic compositions and related methods | LCS Advanced Solutions, LLC (US) | 2024-08-13 | — | — | US | disclosed |
| US-20240122826-A1 | STRUCTURALLY DIVERSE, STABLE, AND RADIATION-PROTECTIVE PARTICLE MATRIX SUNSCREEN AND COSMETIC COMPOSITIONS AND RELATED METHODS | LCS Advanced Solutions, LLC | 2024-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021025-A1 | STRUCTURALLY DIVERSE, STABLE, AND RADIATION-PROTECTIVE PARTICLE MATRIX SUNSCREEN AND COSMETIC COMPOSITIONS AND RELATED METHODS | CYP24A1, TSLP, BRCA1 | TP53 9/4885LMNA 775/4885CYP3A4 1102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.