Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28295786 | 0.85 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL1408579 | 0.83 | — | — | |
| SCHEMBL9545994 | 0.81 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL544590 | 0.81 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL991364 | 0.79 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL28549177 | 0.79 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL26503 | 0.79 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL865527 | 0.79 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL6285624 | 0.78 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL13583601 | 0.78 | TSHR (0.52) | TSHRHPGDTHRBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108139538-B | Composition is used in optical waveguide formation | 日产化学工业株式会社 | 2019-11-05 | — | — | CN | disclosed |
| CN-109791225-A | Antidazzle hard coating laminated body | 日产化学株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-108139538-A | Optical waveguide formation composition | 日产化学工业株式会社 | 2018-06-08 | — | — | CN | disclosed |